Alkalinisation of prilocaine for intravenous regional anaesthesia. Suitability for clinical use

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Comparison of mepivacaine and lidocaine for intravenous regional anaesthesia: pharmacokinetic study and clinical correlation.

BACKGROUND Limitations to the use of lidocaine for intravenous regional anaesthesia (IVRA) include lack of optimal intraoperative analgesia and systemic toxic reactions. This randomized double-blind study was conducted to compare intraoperative and postoperative analgesia, adverse effects, and plasma concentrations of mepivacaine or lidocaine, on release of the tourniquet in patients undergoing...

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Comparison of the disposition kinetics of lidocaine and (+/-)prilocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.

OBJECTIVE The aim of this investigation was to compare the pharmacokinetics of lidocaine and prilocaine in two groups of 10 patients undergoing intravenous regional anaesthesia. METHOD The study had a randomized design. The patients were allocated to one of the two groups of 10. Each group received either lidocaine (200 mg = 0.855 mM) or prilocaine (Citanest, 200 mg = 0.909 mM), injected intr...

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Regional Anaesthesia by the Intravenous Route.

Foldes, F. F., Molloy, R., McNall, P. G., and Koukal, L. R. (1960). 1. Amer. med. Ass., 172, 1493. Geddes, I. C. (1958). Anaesthesia, 13, 200. Holmes, C. M. (1963). Lancet, 1, 245. Hooper, R. L. (1964). Canad. Anaesth. Soc. Y., 11, 247.. Macgregor, J. D. (1960). Lancet, 1, 528. Moore, D. C., and Bridenbaugh, L. D. (1960). 7. Amer. med. Ass., 174, 842. Morrison, J. T. (1931). Brit. 7. Surg., 18,...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 1990

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.1990.tb14622.x